BDBM50259244 CHEMBL4076393::US10266550, Compound 16
SMILES N[C@H]1CCN(C1)c1c(F)cc2c3c1oc1cc(ccc1n3cc(C(O)=O)c2=O)[N+]([O-])=O
InChI Key InChIKey=MDXFAQWIWGBZRL-VIFPVBQESA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50259244
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human topoisomerase-2alpha assessed as reduction in enzyme-mediated decatenation using kinetoplast DNA as substrate after 15 mins by et...More data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+3nMAssay Description:Human Topoisomerase IIα assays were carried out by adding the compounds to 185 ng of kinetoplast DNA (kDNA, from TopoGen) in the buffer supplied...More data for this Ligand-Target Pair